The tires are used for heavy equipment in industries like mining and construction.
The new plant will be Michelin's ninth in South Carolina. More than a third of Michelin's 22,000 North American employees work in the state.
Michelin North America Chairman Pete Selleck praised the state's pro-business climate and the productivity of South Carolina employees.
Michelin is the third big tire company to expand operations in South Carolina in the past year.