The tire allocation has been tweaked for the Monte Carlo event, where drivers will have two sets of each tire compound. Previously, drivers had three sets of the harder compound and one set of softs for the weekend. The requirement that drivers save a set of the harder tires for the sprint race has also been dropped for this weekend.
Pirelli is hoping the new rules will generate a greater variety of strategies during the races.
"The new tire rules for GP2 are an exciting development that will introduce a bigger element of tire strategy and management to the race weekend, making the GP2 Series even better preparation for the very pinnacle of racing," said Pirelli's racing manager Mario Isola.
"With two sets of the softer compound available to them at any point in Monaco, the GP2 drivers will need to think really carefully about when to use them, but they will end up with more experience of running on a faster compound, which needs to be wisely managed."